A protein of the metallo-hydrolase/oxidoreductase superfamily with both beta-lactamase and ribonuclease activity is linked with translation in giant viruses

Proteins with a metallo-beta-lactamase (MBL) fold have been largely studied in bacteria in the framework of resistance to beta-lactams, but their spectrum of activities is broader. We show here that the giant Tupanvirus also encodes a MBL fold-protein that has orthologs in other giant viruses, a dee...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Colson, Philippe, Pinault, Lucile, Azza, Said, Armstrong, Nicholas, Chabriere, Eric, La Scola, Bernard, Pontarotti, Pierre, Raoult, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729979/
https://ncbi.nlm.nih.gov/pubmed/33303919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78658-8
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