Human metallo-β-lactamase enzymes degrade penicillin

Nonribosomal peptides are assemblages, including antibiotics, of canonical amino acids and other molecules. β-lactam antibiotics act on bacterial cell walls and can be cleaved by β-lactamases. β-lactamase activity in humans has been neglected, even though eighteen enzymes have already been annotated...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Diene, Seydina M., Pinault, Lucile, Keshri, Vivek, Armstrong, Nicholas, Khelaifia, Saber, Chabrière, Eric, Caetano-Anolles, Gustavo, Colson, Philippe, La Scola, Bernard, Rolain, Jean-Marc, Pontarotti, Pierre, Raoult, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704141/
https://ncbi.nlm.nih.gov/pubmed/31434986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48723-y
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