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Advantages of brain penetrating inhibitors of kynurenine-3-monooxygenase for treatment of neurodegenerative diseases

Kynurenine-3-monooxygenase (KMO) is an important therapeutic target for several brain disorders that has been extensively studied in recent years. Potent inhibitors towards KMO have been developed and tested within different disease models, showing great therapeutic potential, especially in models o...

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Detalles Bibliográficos
Publicado en:Arch Biochem Biophys
Autores principales: Zhang, Shaowei, Collier, Mary E.W., Heyes, Derren J., Giorgini, Flaviano, Scrutton, Nigel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111166/
https://ncbi.nlm.nih.gov/pubmed/33275878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2020.108702
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