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MHC-E-restricted CD8+ T cells target Hepatitis B virus-infected human hepatocytes

Currently 247 million people are living with chronic HBV infection (CHB), and the development of novel curative treatments is urgently needed. Immunotherapy is an attractive approach to treat CHB, yet therapeutic approaches to augment the endogenous HBV-specific T cell response in CHB patients have...

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Pubblicato in:J Immunol
Autori principali: Burwitz, Benjamin J., Hashiguchi, Patrick K., Mansouri, Mandana, Meyer, Christine, Gilbride, Roxanne M., Biswas, Sreya, Womack, Jennie L., Reed, Jason S., Wu, Helen L., Axthelm, Michael K., Hansen, Scott G., Picker, Louis J., Früh, Klaus, Sacha, Jonah B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109620/
https://ncbi.nlm.nih.gov/pubmed/32161099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900795
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