MHC-E-restricted CD8+ T cells target Hepatitis B virus-infected human hepatocytes

Currently 247 million people are living with chronic HBV infection (CHB), and the development of novel curative treatments is urgently needed. Immunotherapy is an attractive approach to treat CHB, yet therapeutic approaches to augment the endogenous HBV-specific T cell response in CHB patients have...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Burwitz, Benjamin J., Hashiguchi, Patrick K., Mansouri, Mandana, Meyer, Christine, Gilbride, Roxanne M., Biswas, Sreya, Womack, Jennie L., Reed, Jason S., Wu, Helen L., Axthelm, Michael K., Hansen, Scott G., Picker, Louis J., Früh, Klaus, Sacha, Jonah B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109620/
https://ncbi.nlm.nih.gov/pubmed/32161099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900795
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