Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex-E

Major histocompatibility complex (MHC)-E is a highly conserved, ubiquitously expressed, non-classical MHC-Ib molecule with limited polymorphism primarily involved in NK cell regulation. We found that vaccination of rhesus macaques (RM) with ΔRh157.5/.4 Rhesus Cytomegalovirus (RhCMV) vectors results...

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Publicado en:Science
Main Authors: Hansen, Scott G., Wu, Helen L., Burwitz, Benjamin J., Hughes, Colette M., Hammond, Katherine B., Ventura, Abigail B., Reed, Jason S., Gilbride, Roxanne M., Ainslie, Emily, Morrow, David W., Ford, Julia C., Selseth, Andrea N., Pathak, Reesab, Malouli, Daniel, Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Gillespie, Geraldine M., Walters, Lucy C., Brackenridge, Simon, Sharpe, Hannah R., López, César A., Früh, Klaus, Korber, Bette T., McMichael, Andrew J., Gnanakaran, S., Sacha, Jonah B., Picker, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769032/
https://ncbi.nlm.nih.gov/pubmed/26797147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9475
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