Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex-E

Major histocompatibility complex (MHC)-E is a highly conserved, ubiquitously expressed, non-classical MHC-Ib molecule with limited polymorphism primarily involved in NK cell regulation. We found that vaccination of rhesus macaques (RM) with ΔRh157.5/.4 Rhesus Cytomegalovirus (RhCMV) vectors results...

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Vydáno v:Science
Hlavní autoři: Hansen, Scott G., Wu, Helen L., Burwitz, Benjamin J., Hughes, Colette M., Hammond, Katherine B., Ventura, Abigail B., Reed, Jason S., Gilbride, Roxanne M., Ainslie, Emily, Morrow, David W., Ford, Julia C., Selseth, Andrea N., Pathak, Reesab, Malouli, Daniel, Legasse, Alfred W., Axthelm, Michael K., Nelson, Jay A., Gillespie, Geraldine M., Walters, Lucy C., Brackenridge, Simon, Sharpe, Hannah R., López, César A., Früh, Klaus, Korber, Bette T., McMichael, Andrew J., Gnanakaran, S., Sacha, Jonah B., Picker, Louis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769032/
https://ncbi.nlm.nih.gov/pubmed/26797147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9475
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