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SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
The breast cancer type I susceptibility protein (BRCA1) and BRCA1-associated RING domain protein I (BARD1) heterodimer promote genome integrity through pleiotropic functions, including DNA double-strand break (DSB) repair by homologous recombination (HR). BRCA1-BARD1 heterodimerization is required f...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8108010/ https://ncbi.nlm.nih.gov/pubmed/33789098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108921 |
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