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MST1 Promotes Apoptosis through Regulating Sirt1-dependent p53 Deacetylation
Mammalian Sterile 20-like kinase 1 (MST1) protein kinase plays an important role in the apoptosis induced by a variety of stresses. The MST1 is a serine/threonine kinase that is activated upon apoptotic stimulation, which in turn activates its downstream targets, JNK/p38, histone H2B and FOXO. It ha...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044949/ https://ncbi.nlm.nih.gov/pubmed/21212262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182543 |
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