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Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

The protein kinase mammalian sterile 20-like kinase 1 (MST1) is a mammalian homologue of the Drosophila hippo and plays a critical role in regulation of programmed cell death. MST1 exerts pro-apoptotic function through cleavage, autophosphorylation-Thr(183) and subsequent translocation to the nucleu...

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Bibliografische gegevens
Hoofdauteurs: Yuan, Zengqiang, Kim, Donghwa, Shu, Shaokun, Wu, Junbing, Guo, Jianping, Xiao, Lei, Kaneko, Satoshi, Coppola, Domenico, Cheng, Jin Q.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823523/
https://ncbi.nlm.nih.gov/pubmed/19940129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059675
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