Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

The protein kinase mammalian sterile 20-like kinase 1 (MST1) is a mammalian homologue of the Drosophila hippo and plays a critical role in regulation of programmed cell death. MST1 exerts pro-apoptotic function through cleavage, autophosphorylation-Thr(183) and subsequent translocation to the nucleu...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yuan, Zengqiang, Kim, Donghwa, Shu, Shaokun, Wu, Junbing, Guo, Jianping, Xiao, Lei, Kaneko, Satoshi, Coppola, Domenico, Cheng, Jin Q.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823523/
https://ncbi.nlm.nih.gov/pubmed/19940129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.059675
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares