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SIRT1: Regulator of p53 Deacetylation
The cellular NAD(+)/NADH level controls Sir2 (silent information regulator 2) deacetylase activity in regulating aging in lower species. Much work has been put forth to identify ways to activate SIRT1, the mammalian ortholog of Sir2. The identification of p53 as a bona fide substrate of SIRT1 deacet...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
SAGE Publications
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764473/ https://ncbi.nlm.nih.gov/pubmed/24020002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601913484496 |
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