MST1 Promotes Apoptosis through Regulating Sirt1-dependent p53 Deacetylation

Mammalian Sterile 20-like kinase 1 (MST1) protein kinase plays an important role in the apoptosis induced by a variety of stresses. The MST1 is a serine/threonine kinase that is activated upon apoptotic stimulation, which in turn activates its downstream targets, JNK/p38, histone H2B and FOXO. It ha...

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Bibliografiske detaljer
Main Authors: Yuan, Fang, Xie, Qi, Wu, Junbing, Bai, Yujie, Mao, Beibei, Dong, Yongli, Bi, Wenzhi, Ji, Guangju, Tao, Wufan, Wang, Yan, Yuan, Zengqiang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044949/
https://ncbi.nlm.nih.gov/pubmed/21212262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182543
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