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SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer
Chemoresistance is one of the most important challenges in the clinical management of lung cancer. SIRT1 is a NAD dependent protein deacetylase and implicated in diverse cellular processes such as DNA damage repair, and cancer progression. SIRT1 is upregulated in chemoresistant lung cancer cells, ge...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494911/ https://ncbi.nlm.nih.gov/pubmed/31043584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1592-3 |
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