Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance

Background & Aims: Dysregulation of metabolism plays an important role in the development and progression of cancers, while the underlying mechanisms remain largely unknown. This study aims to explore the regulation and relevance of glycolysis in chemoresistance of gastric cancer. Methods: Bioch...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Xu, Jinye, Shi, Qiqi, Xu, Wenxia, Zhou, Qiyin, Shi, Rongkai, Ma, Yanning, Chen, Dingwei, Zhu, Liyuan, Feng, Lifeng, Cheng, Alfred Sze-Lok, Morrison, Helen, Wang, Xian, Jin, Hongchuan
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568185/
https://ncbi.nlm.nih.gov/pubmed/31244938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.31301
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