Metabolic enzyme PDK3 forms a positive feedback loop with transcription factor HSF1 to drive chemoresistance

Background & Aims: Dysregulation of metabolism plays an important role in the development and progression of cancers, while the underlying mechanisms remain largely unknown. This study aims to explore the regulation and relevance of glycolysis in chemoresistance of gastric cancer. Methods: Bioch...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Xu, Jinye, Shi, Qiqi, Xu, Wenxia, Zhou, Qiyin, Shi, Rongkai, Ma, Yanning, Chen, Dingwei, Zhu, Liyuan, Feng, Lifeng, Cheng, Alfred Sze-Lok, Morrison, Helen, Wang, Xian, Jin, Hongchuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6568185/
https://ncbi.nlm.nih.gov/pubmed/31244938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.31301
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