Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes

Macrophages are highly plastic, key regulators of inflammation. Deregulation of macrophage activation can lead to excessive inflammation as seen in inflammatory disorders like atherosclerosis, obesity, multiple sclerosis and sepsis. Targeting intracellular metabolism is considered as an approach to...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Verberk, Sanne G. S., van der Zande, Hendrik J. P., Baardman, Jeroen, de Goede, Kyra E., Harber, Karl J., Keuning, Eelco D., Lambooij, Joost M., Otto, Frank, Zawistowska-Deniziak, Anna, de Vries, Helga E., de Winther, Menno P. J., Guigas, Bruno, Van den Bossche, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107722/
https://ncbi.nlm.nih.gov/pubmed/33981315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.669920
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