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Myeloid-Specific Acly Deletion Alters Macrophage Phenotype In Vitro and In Vivo without Affecting Tumor Growth
SIMPLE SUMMARY: Tumor cells show different metabolism compared to normal tissue. For instance, they increase ATP-citrate lyase (Acly) expression for increased proliferation. Acly is therefore currently being targeted for cancer therapy. However, targeting this enzyme may have side effects on other c...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cancers (Basel) |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
MDPI
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8235155/ https://ncbi.nlm.nih.gov/pubmed/34205266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123054 |
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