Tissue‐specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models

The two insulin receptor (IR) isoforms IR‐A and IR‐B are responsible for the pleiotropic actions of insulin and insulin‐like growth factors. Consequently, changes in IR isoform expression and in the bioavailability of their ligands will impact on IR‐mediated functions. Although alteration of IR isof...

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Pubblicato in:J Cell Mol Med
Autori principali: Moruzzi, Noah, Lazzeri‐Barcelo, Francesca, Valladolid‐Acebes, Ismael, Moede, Tilo, Paschen, Meike, Leibiger, Barbara, Berggren, Per‐Olof, Leibiger, Ingo B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107091/
https://ncbi.nlm.nih.gov/pubmed/33742502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16452
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