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Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice

The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and maintain morphological features of native islets as we...

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Bibliografiske detaljer
Udgivet i:Metabolites
Main Authors: Leibiger, Barbara, Moede, Tilo, Valladolid-Acebes, Ismael, Paschen, Meike, Visa, Montse, Leibiger, Ingo B., Berggren, Per-Olof
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231910/
https://ncbi.nlm.nih.gov/pubmed/34198579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11060387
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