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Tissue‐specific expression of insulin receptor isoforms in obesity/type 2 diabetes mouse models

The two insulin receptor (IR) isoforms IR‐A and IR‐B are responsible for the pleiotropic actions of insulin and insulin‐like growth factors. Consequently, changes in IR isoform expression and in the bioavailability of their ligands will impact on IR‐mediated functions. Although alteration of IR isof...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Moruzzi, Noah, Lazzeri‐Barcelo, Francesca, Valladolid‐Acebes, Ismael, Moede, Tilo, Paschen, Meike, Leibiger, Barbara, Berggren, Per‐Olof, Leibiger, Ingo B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8107091/
https://ncbi.nlm.nih.gov/pubmed/33742502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16452
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