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Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes

Loss of pancreatic β-cell function is a critical event in the pathophysiology of type 2 diabetes. However, studies of its underlying mechanisms as well as the discovery of novel targets and therapies have been hindered due to limitations in available experimental models. In this study we exploited t...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Mir-Coll, Joan, Moede, Tilo, Paschen, Meike, Neelakandhan, Aparna, Valladolid-Acebes, Ismael, Leibiger, Barbara, Biernath, Adelinn, Ämmälä, Carina, Leibiger, Ingo B., Yesildag, Burcak, Berggren, Per-Olof
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918101/
https://ncbi.nlm.nih.gov/pubmed/33670429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041813
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