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Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes

Loss of pancreatic β-cell function is a critical event in the pathophysiology of type 2 diabetes. However, studies of its underlying mechanisms as well as the discovery of novel targets and therapies have been hindered due to limitations in available experimental models. In this study we exploited t...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Mir-Coll, Joan, Moede, Tilo, Paschen, Meike, Neelakandhan, Aparna, Valladolid-Acebes, Ismael, Leibiger, Barbara, Biernath, Adelinn, Ämmälä, Carina, Leibiger, Ingo B., Yesildag, Burcak, Berggren, Per-Olof
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918101/
https://ncbi.nlm.nih.gov/pubmed/33670429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041813
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