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Imidazolium Compounds as Internal Exchange Reporters for Hydrogen/Deuterium Exchange by Mass Spectrometry
Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful tool for protein structure analysis that is well suited for biotherapeutic development and characterization. Because HDX is strongly dependent on solution conditions; even small variations in temperature or pH can have a pronounced...
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| Udgivet i: | Anal Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8106947/ https://ncbi.nlm.nih.gov/pubmed/32569457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c01328 |
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