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High-Precision, Gas-Phase Hydrogen/Deuterium Exchange Kinetics by Mass Spectrometry Enabled by Exchange Standards

Mass spectrometry (MS) has become a primary tool for identifying and quantifying biological molecules. In combination with other orthogonal techniques, such as gas-phase hydrogen/deuterium exchange (gHDX), MS is also capable of probing the structure of ions. However, gHDX kinetics can depend strongl...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Uppal, Sanjit S., Mookherjee, Abhigya, Harkewicz, Rick, Beasley, Sarah E., Bush, Matthew F., Guttman, Miklos
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333526/
https://ncbi.nlm.nih.gov/pubmed/32368904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00749
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