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Imidazolium Compounds as Internal Exchange Reporters for Hydrogen/Deuterium Exchange by Mass Spectrometry

Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful tool for protein structure analysis that is well suited for biotherapeutic development and characterization. Because HDX is strongly dependent on solution conditions; even small variations in temperature or pH can have a pronounced...

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Bibliografske podrobnosti
izdano v:Anal Chem
Main Authors: Murphree, Taylor, Vorauer, Clint, Brzoska, Marie, Guttman, Miklos
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8106947/
https://ncbi.nlm.nih.gov/pubmed/32569457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c01328
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