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Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra

Noisy and overlapped mass spectrometry data hinders the sequence coverage that can be obtained from Hydrogen Deuterium exchange analysis, and places a limit on the complexity of the samples that can be studied by this technique. Advances in instrumentation have addressed these limits, but as the com...

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Autors principals: Guttman, Miklos, Weis, David D., Engen, John R., Lee, Kelly K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855366/
https://ncbi.nlm.nih.gov/pubmed/24018862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-013-0727-5
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