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Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry

Hydrogen deuterium exchange coupled to mass spectrometry (HDX-MS) has emerged as a technique for studying glycoproteins, which are often refractory to classical methods. Glycan chains are generally assumed to exchange protons very rapidly making them invisible to this technique. Here we show that un...

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Bibliografische gegevens
Hoofdauteurs: Guttman, M., Scian, M., Lee, K.K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184328/
https://ncbi.nlm.nih.gov/pubmed/21863800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201729v
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