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Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry
Hydrogen deuterium exchange coupled to mass spectrometry (HDX-MS) has emerged as a technique for studying glycoproteins, which are often refractory to classical methods. Glycan chains are generally assumed to exchange protons very rapidly making them invisible to this technique. Here we show that un...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184328/ https://ncbi.nlm.nih.gov/pubmed/21863800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201729v |
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