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Validation of an Ion Mobility Hydrogen/Deuterium Exchange Mass Spectrometry System
Hydrogen/deuterium exchange mass spectrometry (HXMS) has proven to be a useful analytical method for the study of protein dynamics and changes to protein conformation. Rapid chromatographic separations at 0°C must be utilized to preserve the deuterium label during LC/MS analysis. Unfortunately, fast...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association of Biomolecular Resource Facilities
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186494/ |
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