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Use of Ion Mobility and Fragment Ions to Increase Coverage in Hydrogen-Deuterium Exchange
Peptide signals in H/D exchange mass spectrometry experiments are often overlapping on the m/z scale due to the nonspecific digestion, fast chromatographic conditions, and cold temperatures required to preserve the deuterium label. Co-eluting peptides which are well resolved when undeuterated can ov...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630638/ |
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