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Subzero Celsius separations in three-zone temperature controlled hydrogen deuterium exchange mass spectrometry
Hydrogen deuterium exchange mass spectrometry (HDX MS) reports on the conformational landscape of proteins by monitoring the exchange between backbone amide hydrogen atoms and deuterium in the solvent. To maintain the label for analysis, quench conditions of low temperature and pH are required durin...
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Publicado no: | J Chromatogr A |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675777/ https://ncbi.nlm.nih.gov/pubmed/28596009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2017.05.067 |
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