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High-speed and high-resolution UPLC separation at zero degrees Celsius
The conformational properties of proteins can be probed with hydrogen/deuterium exchange mass spectrometry (HXMS). In order to maintain the deuterium label during LC/MS analyses, chromatographic separation must be done rapidly (usually in under 8–10 minutes) and at zero degrees Celsius. Traditional...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562353/ https://ncbi.nlm.nih.gov/pubmed/18672890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac8008862 |
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