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Gas-phase hydrogen/deuterium exchange in a travelling wave ion guide for the examination of protein conformations
Accumulating evidence suggests that solution-phase conformations of small globular proteins and large molecular protein assemblies can be preserved for milliseconds after electrospray ionization. Thus, the study of proteins in the gas-phase on this time-scale is highly desirable. Here we demonstrate...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794942/ https://ncbi.nlm.nih.gov/pubmed/19921790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901897x |
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