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ETD in a Traveling Wave Ion Guide at Tuned Z-Spray Ion Source Conditions Allows for Site-Specific Hydrogen/Deuterium Exchange Measurements

The recent application of electron transfer dissociation (ETD) to measure the hydrogen exchange of proteins in solution at single-residue resolution (HX-ETD) paves the way for mass spectrometry-based analyses of biomolecular structure at an unprecedented level of detail. The approach requires that a...

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Detalhes bibliográficos
Main Authors: Rand, Kasper D., Pringle, Steven D., Morris, Michael, Engen, John R., Brown, Jeffery M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438897/
https://ncbi.nlm.nih.gov/pubmed/21952892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0196-7
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