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Gas-phase hydrogen/deuterium exchange in a travelling wave ion guide for the examination of protein conformations

Accumulating evidence suggests that solution-phase conformations of small globular proteins and large molecular protein assemblies can be preserved for milliseconds after electrospray ionization. Thus, the study of proteins in the gas-phase on this time-scale is highly desirable. Here we demonstrate...

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Detalhes bibliográficos
Main Authors: Rand, Kasper D., Pringle, Steven D., Murphy, James P., Fadgen, Keith E., Brown, Jeff, Engen, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794942/
https://ncbi.nlm.nih.gov/pubmed/19921790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901897x
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