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Crystal structures of LeuT reveal conformational dynamics in the outward-facing states

The neurotransmitter:sodium symporter (NSS) homolog LeuT from Aquifex aeolicus has proven to be a valuable model for studying the transport mechanism of the NSS family. Crystal structures have captured LeuT in key conformations visited during the transport cycle, allowing for the construction of a n...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Fan, Jianjun, Xiao, Yang, Quick, Matthias, Yang, Yuwei, Sun, Ziyi, Javitch, Jonathan A., Zhou, Xiaoming
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105300/
https://ncbi.nlm.nih.gov/pubmed/33811858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100609
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