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Structural insights into integrin α(5)β(1) opening by fibronectin ligand
Integrin α(5)β(1) is a major fibronectin receptor critical for cell migration. Upon complex formation, fibronectin and α(5)β(1) undergo conformational changes. While this is key for cell-tissue connections, its mechanism is unknown. Here, we report cryo–electron microscopy structures of native human...
Gorde:
| Argitaratua izan da: | Sci Adv |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Association for the Advancement of Science
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8104898/ https://ncbi.nlm.nih.gov/pubmed/33962943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe9716 |
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