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Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor
Integrin α5β1 is a major cellular receptor for the extracellular matrix protein fibronectin and plays a fundamental role during mammalian development. A crystal structure of the α5β1 integrin headpiece fragment bound by an allosteric inhibitory antibody was determined at a 2.9-Å resolution both in t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317794/ https://ncbi.nlm.nih.gov/pubmed/22451694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111077 |
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