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Promoter G-quadruplex folding precedes transcription and is controlled by chromatin
BACKGROUND: Four-stranded G-quadruplexes (G4s) are DNA secondary structures in the human genome that are primarily found in active promoters associated with elevated transcription. Here, we explore the relationship between the folding of promoter G4s, transcription and chromatin state. RESULTS: Tran...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8103603/ https://ncbi.nlm.nih.gov/pubmed/33962653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02346-7 |
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