Analysis of NRAS RNA G-quadruplex binding proteins reveals DDX3X as a novel interactor of cellular G-quadruplex containing transcripts

RNA G-quadruplexes (rG4s) are secondary structures in mRNAs known to influence RNA post-transcriptional mechanisms thereby impacting neurodegenerative disease and cancer. A detailed knowledge of rG4–protein interactions is vital to understand rG4 function. Herein, we describe a systematic affinity p...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Herdy, Barbara, Mayer, Clemens, Varshney, Dhaval, Marsico, Giovanni, Murat, Pierre, Taylor, Chris, D'Santos, Clive, Tannahill, David, Balasubramanian, Shankar
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265444/
https://ncbi.nlm.nih.gov/pubmed/30256975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky861
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