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Chemical profiling of DNA G-quadruplex-interacting proteins in live cells

DNA–protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we describe a co-binding-mediated protein profiling (CMPP) strategy to inves...

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Bibliografiska uppgifter
I publikationen:Nat Chem
Huvudupphovsmän: Zhang, Xiaoyun, Spiegel, Jochen, Martínez Cuesta, Sergio, Adhikari, Santosh, Balasubramanian, Shankar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245323/
https://ncbi.nlm.nih.gov/pubmed/34183817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-021-00736-9
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