DNA G-quadruplex structures mould the DNA methylome

Control of DNA methylation level is critical for gene regulation, and the factors that govern hypomethylation at CpG islands (CGIs) are still being uncovered. Here, we provide evidence that G-quadruplex (G4) DNA secondary structures are genomic features that influence methylation at CGIs. We show th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Struct Mol Biol
मुख्य लेखकों: Mao, Shi-Qing, Ghanbarian, Avazeh T., Spiegel, Jochen, Cuesta, Sergio Martínez, Beraldi, Dario, Di Antonio, Marco, Marsico, Giovanni, Hänsel-Hertsch, Robert, Tannahill, David, Balasubramanian, Shankar
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173298/
https://ncbi.nlm.nih.gov/pubmed/30275516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0131-8
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