G-quadruplexes are transcription factor binding hubs in human chromatin

BACKGROUND: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many questions remain on how binding site specificity is governed. RESULTS: Herein, we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Spiegel, Jochen, Cuesta, Sergio Martínez, Adhikari, Santosh, Hänsel-Hertsch, Robert, Tannahill, David, Balasubramanian, Shankar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063395/
https://ncbi.nlm.nih.gov/pubmed/33892767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02324-z
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