A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a mouse model of rosacea‐like skin inflammation....

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Deng, Zhili, Chen, Mengting, Liu, Yingzi, Xu, San, Ouyang, Yuyan, Shi, Wei, Jian, Dan, Wang, Ben, Liu, Fangfen, Li, Jinmao, Shi, Qian, Peng, Qinqin, Sha, Ke, Xiao, Wenqin, Liu, Tangxiele, Zhang, Yiya, Zhang, Hongbing, Wang, Qian, Sun, Lunquan, Xie, Hongfu, Li, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103105/
https://ncbi.nlm.nih.gov/pubmed/33734592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013560
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