A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a mouse model of rosacea‐like skin inflammation....

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Detaylı Bibliyografya
Yayımlandı:EMBO Mol Med
Asıl Yazarlar: Deng, Zhili, Chen, Mengting, Liu, Yingzi, Xu, San, Ouyang, Yuyan, Shi, Wei, Jian, Dan, Wang, Ben, Liu, Fangfen, Li, Jinmao, Shi, Qian, Peng, Qinqin, Sha, Ke, Xiao, Wenqin, Liu, Tangxiele, Zhang, Yiya, Zhang, Hongbing, Wang, Qian, Sun, Lunquan, Xie, Hongfu, Li, Ji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103105/
https://ncbi.nlm.nih.gov/pubmed/33734592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013560
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