Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)

Despite current pharmacological intervention strategies, patients with HIV still suffer from chronic inflammation. The nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the nervous and immune systems. In macrophages, activation of alpha7-nAChR (α7-nAChR) controls inflammat...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ríos, Sonnieliz Cotto, Colón Sáez, José O., Quesada, Orestes, Figueroa, Katherine Quiroz, Lasalde Dominicci, José A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102909/
https://ncbi.nlm.nih.gov/pubmed/33811859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100618
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