The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders

Currently, there are no specific therapies to treat HIV-1 associated neurocognitive disorders (HAND). The HIV-1 envelope, gp120, induces neuropathological changes similar to those in HAND patients; furthermore, it triggers an upregulation of the α7-nicotinic acetylcholine receptor (α7-nAChR), facili...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Capó-Vélez, Coral M., Morales-Vargas, Bryan, García-González, Aurian, Grajales-Reyes, José G., Delgado-Vélez, Manuel, Madera, Bismark, Báez-Pagán, Carlos A., Quesada, Orestes, Lasalde-Dominicci, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788855/
https://ncbi.nlm.nih.gov/pubmed/29379089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20271-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados