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M-tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T-tropic gp120 in rat striatum

Most early human immunodeficiency virus type 1 (HIV-1) strains are macrophage (M)-tropic HIV variants and use the chemokine receptor CCR5 for infection. Neuronal loss and dementia are less severe among individuals infected with M-tropic strains. However, after several years, the T cell (T)-tropic HI...

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Bibliographic Details
Main Authors: Bachis, Alessia, Cruz, Maria I., Mocchetti, Italo
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924467/
https://ncbi.nlm.nih.gov/pubmed/20670282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07325.x
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