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Endocytic Trafficking of HIV gp120 is Mediated by Dynamin and Plays a Role in gp120 Neurotoxicity

Neurons that endocytose the human immunodeficiency virus-1 (HIV) protein gp120 exhibit neurite retraction and activation of caspase-3, suggesting that the endocytic process may be crucial for gp120-mediated neuronal injury. The goal of this study is to demonstrate that internalization and accumulati...

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Bibliografiske detaljer
Udgivet i:J Neuroimmune Pharmacol
Main Authors: Wenzel, Erin D., Bachis, Alessia, Avdoshina, Valeria, Taraballi, Francesca, Tasciotti, Ennio, Mocchetti, Italo
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815508/
https://ncbi.nlm.nih.gov/pubmed/28349243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-017-9739-4
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