Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)

Despite current pharmacological intervention strategies, patients with HIV still suffer from chronic inflammation. The nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the nervous and immune systems. In macrophages, activation of alpha7-nAChR (α7-nAChR) controls inflammat...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Ríos, Sonnieliz Cotto, Colón Sáez, José O., Quesada, Orestes, Figueroa, Katherine Quiroz, Lasalde Dominicci, José A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102909/
https://ncbi.nlm.nih.gov/pubmed/33811859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100618
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