Disruption of the cholinergic anti-inflammatory response by R5-tropic HIV-1 protein gp120(JRFL)

Despite current pharmacological intervention strategies, patients with HIV still suffer from chronic inflammation. The nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the nervous and immune systems. In macrophages, activation of alpha7-nAChR (α7-nAChR) controls inflammat...

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Vydáno v:J Biol Chem
Hlavní autoři: Ríos, Sonnieliz Cotto, Colón Sáez, José O., Quesada, Orestes, Figueroa, Katherine Quiroz, Lasalde Dominicci, José A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102909/
https://ncbi.nlm.nih.gov/pubmed/33811859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100618
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