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Stereoelectronic Effects in Stabilizing Protein–N-Glycan Interactions Revealed by Experiment and Machine Learning

The energetics of protein-carbohydrate interactions, central to many life processes, cannot yet be predictably manipulated. This is mostly due to an incomplete quantitative understanding of the enthalpic and entropic basis of these interactions in aqueous solution. Here, we show that stereoelectroni...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Ardejani, Maziar S., Noodleman, Louis, Powers, Evan T., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102341/
https://ncbi.nlm.nih.gov/pubmed/33723379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-021-00646-w
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